Electromagnetic Field Therapies: A Bibliography from Medline

Phil Rogers MVB MRCVS
1, Esker Lawns, Lucan, Dublin, Ireland
e-mail : philrogers@tinet.ie

2. Circulation, ischaemia, hypertension,
fibrinolysis, CHD, CVA

Bogdanov NN, Akhmedzhanov MIu, Buiavykh AG (1986) [Optimization of the effects of physical and health resort factors in ischemic heart disease and arterial hypertension - Article in Russian]. Ter Arkh 58(5):108-111. Natural and instrumental physical methods were discussed in the therapy, prevention and rehabilitation of 280 patients with coronary heart disease (CHD) and 300 patients with arterial hypertension (AH). In the CHD and AH patients, short- and long-term follow-up results showed the efficacy of optimized use of a number of physical factors (precardial and segmental massage, low frequency magnetic field). It is appropriate to expand the concept "nonpharmacological" methods in the control of CHD and AH. PMID: 3488602, UI: 86290113

Ezhova LV, Akhmedzhanov MIu, Shatrov AA (1985) [Changes in physical work capacity of patients with myocardial infarction under the effect of graded bicycle training with preliminary action of magnetic field - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Jan;1:58-59. PMID: 3984256, UI: 85169881

Galimzianov FV (1990) [Electromagnetic therapy after phlebectomy - Article in Russian]. Khirurgiia (Mosk) May;5:108-110. Comparative analysis of outpatient treatment by means of pulsed complexly-modulated EMF (PCMEMF) applied after phlebectomy in 30 patients with varicosity of the lower limbs showed the expediency of this type of treatment in the postoperative period. Exposure of the operated on limb to PCMEMF raises the efficacy of the rehabilitation measures and reduces the terms of the patients' temporary incapacity. PMID: 2391917, UI: 90362765

Gorczynska E (1988) Fibrinolytical processes in rabbits activated by the magnetic field. J Hyg Epidemiol Microbiol Immunol 32(4):391-396. Dept of Biochemistry, Academy of Agriculture, Szczecin, Poland. Rabbits were exposed to a constant magnetic field of 0.005 T, 0.1 T and 0.3 T induction for 1 h/d for 28 d. The magnetic field increased the rate of fibrinolysis. A decrease in fibrinogen concentration, an increase in the level of fibrinogen degradation products and a considerably shorter time of fibrinolysis in plasma were all noted. The magnitude of these processes was proportional to duration of exposure to the magnetic field in action. These date confirms the similar effect seen in other mammalians (guinea pigs, rats). Thus, the application of a static magnetic field of intensity as low as 0.005 T to increase a fibrinolysis in the thrombotic therapy seems to be justified. PMID: 3221089, UI: 89124317

Gordon RT, Gordon D (1981) Selective resolution of plaques and treatment of atherosclerosis by biophysical alteration of "cellular" and "intracellular" properties. Med Hypotheses Feb;7(2):217-229. This is a totally new approach to effective treatment of atherosclerosis by alteration of biophysical properties both "intracellularly" and "extracellularly." Early results show that by allowing the atherosclerotic lesions to take up the magnetically excitable submicron particles and then applying an external alternating EMF, the atherosclerotic lesions may be selectively resolved without damaging normal blood vessels. This concept suggests many areas of research since there are many ways to alter atherosclerotic plaques biophysically, and many substances may be used to enhance the process. This new technology and this initial experimentation introduces a "new era" in the effective treatment of Atherosclerosis. PMID: 7219246, UI: 81172377

Grant G, Cadossi R, Steinberg G (1994) Protection against focal cerebral ischemia following exposure to a pulsed EMF. Bioelectromagnetics 15(3):205-216. Dept of Neurosurgery, Stanford Univ, California 94305. There is evidence that EM stimulation may accelerate the healing of tissue damage after ischemia. We studied the effects of low frequency PEMF exposure on cerebral injury in a rabbit model of transient focal ischemia (2 h occlusion followed by 4 h of reperfusion). PEMF exposure (280 V, 75 Hz, IGEA Stimulator) was initiated 10 min after the onset of ischemia and continued throughout reperfusion (6 exposed, 6 controls). MRI and histology were used to measure the degree of ischemic injury. Exposure to PEMF attenuated cortical ischemia edema on MRI at the most anterior coronal level by 65% (p<.001). On histology, PEMF exposure reduced ischemic neuronal damage in this same cortical area by 69% (p<.01) and by 43% (p<.05) in the striatum. Exposure to a PEMF of short duration may have implications for the treatment of acute stroke. PMID: 8074737, UI: 94354894

Grunner O (1985) [Cerebral use of a pulsating magnetic field in neuropsychiatry patients with long-term headache - Article in German]. EEG EMG Z Elektroenzephalogr Verwandte Geb Dec;16(4):227-230. 40 patients with headaches of various etiology were given pulsed magnetic field therapy (f=260 Hz; t=3 ms; induction B=1.9 mT; gradient=0.5 mT/cm). Each session lasted 0.5 h. Self-assessment statements and EEG changes were used to evaluate changes of headache intensity. EEG frequency analysis showed significant changes in % delta and alpha 1 activities (7.5-9.5/s) after use of the real treatment, as compared with sham treatment. Improved self-assessment, and EEG were found in headaches associated with cerebral arteriosclerosis, sequels to cerebral concussion, depressive neurosis, or tension headache. Pulsed magnetic field could be applied only where the EEG was physiological. PMID: 3935419, UI: 86081440

Karlov VA, Rodshtat IV, Kalashnikov IuD, Kitaeva LV, Khokhlov IuK (1991) [Experience with using extremely high frequency radiotherapy of the millimeter wave range in cerebrovascular disorders - Article in Russian]. Sov Med 3:20-21. Vascular diseases of the brain (functional transient and ischemic apoplexy, circulatory encephalopathy) in 79 patients were treated by UHF EMF of millimetric wave range. 14 patients entered the control group. The data show a clear-cut trend to a decrease of arterial pressure, normalization of blood glucose level, arrest of DIC syndrome development. PMID: 1882282, UI: 91352655

Kniazeva TA, Otto MP, Markarov GS, Donova OM, Markarova IS (1994) [The efficacy of low-intensity exposures in hypertension - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Jan;1:8-9. 100 hypertensive subjects with labile and stable disease were exposed to low-intensity low-frequency electrostatic field generated by the unit "Infita-A". In labile hypertension, the field produces a hypotensive effect, improves myocardial contractility, increases myocardial and coronary reserves due to reduced peripheral resistance and stimulation of myocardial propulsion. Therapeutic response to the treatment is attributed to normalized function of deep brain structures. PMID: 8171859, UI: 94225808

Kniazeva TA (1979) [Effect of a decimeter-band EMF on the functional state of the kidneys and on renal and central hemodynamics in the period of rehabilitative postoperative treatment of renovascular hypertension - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult 3:36-41. PMID: 473667, UI: 79251078

Liubimova NN, Popov VI (1990) [The action of a decimeter-wave EMF on the indices of the blood kallikrein-kinin system in rabbits with an experimental myocardial infarct - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult May;3:14-17. Continuous 10-d exposure of the heart and adrenal regions of rabbits with myocardial infarction to EMF produced by decimeter waves leads to activation of kallikrein-kinin system. With the heart exposure, this activation comes through marked changes in microcirculatory bed, whereas in the adrenal exposure it is trophic defects that are induced in the myocardium. The exposure of the thyroid regions brings about unnoticeable effect. PMID: 2219809, UI: 91021141

Lud GV (1986) [Effect of a constant magnetic field on blood circulation after experimental operations on arteries of the extremities - Article in Russian]. Vestn Khir Sep;137(9):87-88. PMID: 3538626, UI: 87071468

Miasnikov IG (1992) [Magnetotherapy of initial manifestations of cerebrovascular disorders in hypertension - Article in Russian]. Zh Nevropatol Psikhiatr Im S S Korsakova 92(1):63-67. The paper is concerned with the data on 147 subjects who underwent magnetotherapy with the unit "Magniter-AMT-01" applied to the cervical area. The main group included 102 subjects, 45 person served as control. The purpose of the work was to base the application of MT under inpatient and home conditions with the use of the above-indicated unit. In view of this fact, a study was made of cerebral hemo- and thermodynamics with the aid of rheoencephalography and encephaloradiothermography under the action of different modes of the functioning of the unit "Magniter-AMT-01" (pulse and variable magnet induction fields 12-15 mTl and 30-35 mTl). A method of measuring magnetosensitivity of patients depending on the temperature reaction of the brain to a single MT session was elaborated. The greatest clinical effect was attained with the use of pulse magnetic field 15 mTl. Magnetotherapy with the use of the unit "Magniter-AMT-01" gave good results under inpatient and home conditions. The magnetosensitive patients had the highest effect. PMID: 1319653, UI: 92312254

Orlov LL, Alekseeva NP, Slutskii II, Galuza GI, Chogovadze VA (1986) [Various humoral factors regulating blood pressure in patients with hypertension during treatment by an impulse magnetic field - Article in Russian]. Kardiologiia Mar;26(3):56-60. Renin activity, aldosterone, prostaglandin (PGF2 alpha and PGB) and cyclic nucleotide levels and catecholamine excretion were measured in 165 essentially hypertensive patients exposed to therapeutic effects of "running" impulse magnetic field (RIMF). The correction of arterial blood pressure in RIMF-treated patients was mediated by BP-controlling humoral factors, the magnitude and direction of changes in levels and activity of biologically-active substances and hormones being determined by their respective baselines. A decrease of hyperfunction, as reflected in elevated hormonal production, and an increase of hypofunction were the most common therapeutic effect of RIMF exposure. PMID: 3012184, UI: 86228610

Orlov LL, Makoeva LD, Glezer MG, Memetov KA, Belinskaia TF, Arzhanenko OM (1991) [Effects of impulse magnet field and beta adrenergic blockaders on physical work capacity and hemodynamics of patients with neurocirculatory dystonia of the cardiac type - Article in Russian]. Kardiologiia Feb;31(2):36-39. PMID: 2041288, UI: 91251499

Orlov LL, Makoeva LD, Glezer MG, Titov SIu, Arzhanenko OM, Margarian AG, Musev VA, Memetov KA, Belinskaia TF (1992) [Evaluation of antianginal effects of running pulse magnetic field and drug therapy on the physical working capacity and hemodynamics in patients with stable angina pectoris - Article in Russian]. Kardiologiia Feb;32(2):23-26. The effects of the running pulse magnetic field, antianginal drug therapy and their combinations on the physical capacity were compared in 60 patients with Functional Classes I-III stable angina pectoris. Monotherapy with the running pulse magnetic field was found to produce an antianginal effect in patients with Functional Classes I-II angina pectoris, but the efficacy of drug therapy increased when antianginal drugs were used in combination with running pulse magnetic field in patients with severe angina. PMID: 1527930, UI: 92408123

Orlov LL, Alekseeva NP, Galuza GI, Slutskii II, Drozdov IuF (1985) [Hemodynamic and humoral mechanisms of the therapeutic effect of the "travelling" impulse magnetic field in hypertension - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Jan;1:23-27. PMID: 3984249, UI: 85169867

Pasynkov EI, Konstantinova GD, Vlasova EI (1976) [Therapeutic use of alternating magnetic field in chronic diseases of the veins of the lower limbs - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Sep;5:16-19. PMID: 1025854, UI: 77176520

Shatrov AA (1978) [Effect of sanatorium-health resort treatment with the inclusion of a UHF electrical field and centimer-range electromagnetic waves on the peripheral blood circulation and vascular reactivity of patients with vibration disease - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Mar;2:22-25. PMID: 148780, UI: 78182266

Sokolov BA, Bezruchenko SV, Kunitsyna LA (1998) [A comparative evaluation of the effect of an extremely high-frequency EMF on cerebral hemodynamics in hypertension patients exposed in different reflexogenic areas - Article in Russian]. Vopr Kurortol Fizioter Lech Fiz Kult Jan;1:16-18. A single session and multiple sinocarotid and temporal exposures to EHF EMF in patients with stage I and II hypertension had different effects on cerebral circulation. Variants of the above treatment are proposed. PMID: 9560995, UI: 98221766

Strelkova NI, Gavrilkov AT, Diuzhilova NF, Strel'tsova EN (1981) [Status of cerebral circulation in patients with hemiplegia of vascular and traumatic origin treated with decimeter therapy and an alternating magnetic field - Article in Russian]. Zh Nevropatol Psikhiatr 81(8):1162-1166. 181 patients with hemiparesis after a cerebral stroke or craniocerebral injury were treated by local exposure of the pathological focus to decimeter EM waves (DW) and alternating magnetic field (AMF). These treatment methods improved the cerebral circulation and hastened the restoration of motor functions, especially, if used in combination with sulfide baths, therapeutic physical exercises and massage. The therapeutic effectiveness of the DW- and AMF-therapy is confirmed objectively by so informative examination methods, as rheoencephalography, ultrasonic dopplerography, and thermography. PMID: 7315051, UI: 82087133

Strelkova NI, Maslovskaia SG, Gavrilkov AG, Strel'tsova EN (1983) [Use of the EMF in patients after disturbance of cerebral circulation - Article in Russian]. Sov Med 5:35-38. PMID: 6612459, UI: 83302409

Temur'iants NA, Mikhailov AV (1985) [Effect of weak alternating ultra-low frequency magnetic fields on the development of the hypercoagulation syndrome in immobilized rats - Article in Russian]. Biofizika Nov;30(6):1046-1049. The experimental results are given concerning the effect of variable magnetic field (VMF) with the frequency of 8 Hz and intensity 4 A/m on some parameters of rat haemocoagulation system under standard mobile regime as well as under prolonged hypokinesia. It is stated that repeated daily exposition of VMF causes hypocoagulational blood shift in intact animals. Under the effect of simultaneous VMF and hypokinesia the correction of hypercoagulational shift induced by animal hypokinesia was found. The highest VMF effect was seen in prolonged experiments. The ability of VMF with the given parameters to limit the development of rat blood hypercoagulation under hypokinesia was discussed. PMID: 4074760, UI: 86077826