AP and the Cardiovascular System
CORONARY HEART DISEASE (CHD)
Li_L; Chen H; Xi Y; Wang X; Han G; Zhou Y; Yang D; Zhao W; Feng Z; Jiao B et al (1994) Comparative observation on effect of electric AP of PC06 at Chen time versus Xu time on left ventricular function in patients with CHD. Chung i tsa chih (JTCM) Dec 14(4):262-265. Shanghai TCM Coll. Paired experimental design was used to compare the effect on left ventricular function in patients with CHD of EAP of PC06 at Chen Time (0700-0900h, the "Full" time for ST) versus Xu Time (1900-2100h, the "Empty" time for ST). As indicated by shortening of PEPI and decrease of PEPI/LVETI ratio, EAP at circa 0800h improved left ventricular function of CHD patients. However, as indicated by prolonged PEPI and raised PEPI/LVETI ratio in CHD patients, EAP at circa 2000h impaired left ventricular function.
Liu_J3; Han Z; Cao Q; Chen S (1994) Influence of thoracic spinal subarachnoid microinjection of phentolamine on the effect of EAP. Chen Tzu Yen Chiu - AP Research 19(2):47-51. Inst of AP & Moxibustion, China Acad of TCM, Beijing, PRC. The influence of thoracic spinal subarachnoid microinjection of Phentolamine (Phen, 200ug/20ul) on the effect of EAP at PC06 was observed in 42 urethan-chloralose anaesthetized rabbits. EAP of PC06 significantly promoted recovery of elevated ST-segments and T-waves of electrocardiogram induced by acute myocardial ischemia (AMI). Subarachnoid microinjection of phentolamine had no marked influence on recovery of ST-segments and T-waves, but impeded recovery of blood pressure of post-AMI. Subarachnoid microinjection of phentolamine significantly weakened or eliminated the effect of EAP of PC06 in accelerating recovery of ST-segments and T-waves of post-AMI. Alpha-receptors of intra-thoracic spinal cord participate in the action of EAP of PC06 in improving AMI, and the upper thoracic spinal cord segment is one of the links connecting PC06 and the heart.
Liu_J4; Han Z; Chen S; Cao Q (1996) Influence of EAP of PC06 on AMI-induced changes in electrical activity of dorsal horn neurons. Inst of AP and Moxibustion, China Acad of TCM, Beijing, PRC. Adapted from WWW. The electrical activity of the dorsal horn (DH) neurons was recorded extracellularly by glass micro-pipettes in urethane-chloralose anaesthetized rabbits to analyze the role of the thoracic segments (T2-T3) of the spinal cord in the integration of information from EAP at PC06 and acute myocardial ischemia (AMI).
Results:
1. after AMI, of 83 DH neurons, 18 showed a significant excitatory response, 14 an obvious inhibitory reaction and 51 no apparent change;
2. after EAP at PC06, of 10 neurons with AMI-induced excitatory response, the electrical activity of 9 neurons was suppressed and the other 1 still maintained its excitatory state; of 8 neurons with AMI-induced inhibitory response, 7 were relieved from the suppressed state, the other 1 had no change after EAP;
and 3. the receptive field and the responsive types to somatic stimulation were examined in 83 DH neurons.
Signals from EAP at PC06 and AMI converge to the DH neurons of T2-T3. DH participates in the integrative course of information from EAP and AMI and thus it is one of the connective links between PC06 and the heart.
Saku_K; Mukaino Y; Ying H; Arakawa K (1993) Characteristics of reactive electropermeable points on the Ears of CHD patients. Clin Cardiol May 16(5):415-419. Dept of Internal Med, Fukuoka Univ Sch of Med, Japan. In TCM/AP, Earpoints relate to every part of the human body by a projection of functional neuroanatomy. Using a neurometer LC-M, we studied reactive electropermeable points (REPP, points on the skin with low electrical resistance), on the Ear of patients with CHD. We found REPP points which correlated positively with special Earpoints found by Chinese workers to relate cardiac functional anatomy. These points were HT-1 (Xin) and HT-2 (Xinzo). Patients with AMI had an extremely high incidence of positive REPP points at Xin and Xinzo; patients with old myocardial infarction (OMI) and angina pectoris also had a significant number of positive REPPs in those areas. The incidence rates of REPP at Xin and Xinzo points between the OMI and angina groups were not significantly different. High incidence of positive REPP points at the LU and HT-3 (Xinshu) points occurred only in the AMI group; this was significantly high when compared with the control group.
Shi X (1996) Effect of AP on Heart Rate Variability in CHD Patients. Shi Xian, Heilongjiang College of TCM, Harbin 150040. PRC. Adapted from WWW at http://www.dmu.ac.uk/ln/cmn/fmdc@public3.bta.net.cn (Chin Med News, Beijing Cons Bio-Tech (e-mail: wangyq@sun.ihep.ac.cn). Using frequency domain analysis, heart rate variability (HRV) was measured in 20 CHD patients pre- and post- AP. In two groups of patients, AP at PC06 (by simple needling or by EAP) gave significant changes from pretreatment values for low frequency (LF) HRV-components (p<.05); changes in untreated control patients were not significant (p>.05). Changes in High frequency (HF) HRV-components were not significant in any group. LF/HF change was marked in the EAP group (p<.05); simple needle AP reduced LF to its lowest level in 10 min, without any rebound phenomenon. AP regulated and improved HRV in CHD; as found by many other groups, stimulation of the median nerve has practical applications in cardiology. AP mechanisms relate to CNS regulation and participation of neurotransmitters.
Xie_X2; Zeng Q; Liu X; Zhen Q; Xiao J (1994) Observation on the changes of plasma cardionatrion before and after microwave AP in CHD. Chung i tsa chih (JTCM) Mar 14(1):26-29. Dept of AP, General (301) Hospital of PLA, Beijing, PRC. The therapeutic effect of microwave AP (MWA) and its influence on the plasma level of cardionatrion is reported. 28 cases with CHD were systemically observed and studied. Atrial natriuretic polypeptides (ANP) were determined by RIA. Plasma level of ANP was elevated, the rising rate being 100%. The therapeutic effect of MWA in the 28 cases with CHD was 86%, the ECG improving rate was 82%. Effect of MWA was briefly discussed. The therapeutic effect of MWA to treat CHD was shown. Measurement of plasma ANP level was a useful method and is an objective parameter for further research.
Yin_K; Jia C (1991) Treatment of chronic coronary insufficiency with AP at PC04. JTCM Jun 11(2):99-100. Dept of AP and Moxibustion, Shaanxi College of TCM, PRC.
Zhou_JR1 (1993) Effect of Ear-AP plus needle embedding in HT point on left cardiac, humoral and endocrine function. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih Mar 13(3):153-154, 132. Wuxi First People's Hospital, Jiangsu, PRC. 12 patients with dilating cardiomyopathy complicated heart failure were assigned at random to 2 groups: 1=Ear-AP (n=7) and; 2=Control (untreated, n=5). Left myocardial function and plasma levels of PRA, ALD, EDLS, ANF were measured. Ear-AP decreased CO, CI, ANF, EDLS and ALD (p <.05). Ear-AP plus needle-embedding in Earpoint HT improved left cardiac function in patients with dilating cardiomyopathy complicated heart failure; the function of specific AP points differs distinctly from other points and from non-points.